PMID- 11549384
DA - 20010910
DCOM- 20011207
IS - 0006-8993
VI - 913
IP - 2
DP - 2001 Sep 21
TI - Dietary soy phytoestrogens produce anxiolytic effects in the elevated plus-maze.
PG - 180-4 AB - Naturally occurring estrogen-like molecules in plants (phytoestrogens), present via soy, in animal diets, exert many of the biological responses evoked by physiological estrogens. This study characterized the effects of dietary phytoestrogens on the expression of body weight, consummatory behavior, and anxiety (as expressed in the elevated plus-maze). Phytoestrogens produced anxiolytic effects in both male and female Long-Evans rats. Additionally, phytoestrogens decreased body weight but increased consumption of food and/or water.
AD - Neuroscience Center, Brigham Young University, Provo, UT 84602, USA.
[emd]
FAU - Lund, T D
AU - Lund TD
FAU - Lephart, E D
AU - Lephart ED
LA - eng
PT - Journal Article
CY - Netherlands
TA - Brain Res
JID - 0045503
RN - 0 (Androgens)
RN - 0 (Anti-Anxiety Agents)
RN - 0 (Estrogens)
RN - 0 (Estrogens, Non-Steroidal)
RN - 0 (phytoestrogens)
SB - IM
MH - Androgens/metabolism
MH - Animal
MH - Anti-Anxiety Agents/*pharmacology
MH - Anxiety/*drug therapy/etiology/physiopathology
MH - Behavior, Animal/drug effects/physiology
MH - Body Weight/drug effects/physiology
MH - Brain/*drug effects/metabolism
MH - Drinking/physiology
MH - Eating/drug effects/physiology
MH - Estrogens
MH - Estrogens, Non-Steroidal/*pharmacology
MH - Female
MH - *Food, Formulated
MH - Male
MH - Maze Learning/*drug effects/physiology
MH - Rats
MH - Rats, Long-Evans
MH - Sex Characteristics
MH - Soybeans/*chemistry
MH - Support, Non-U.S. Gov't
MH - Support, U.S. Gov't, Non-P.H.S.
EDAT- 2001/09/11 10:00
MHDA- 2002/01/05 10:01
AID - S0006899301027937 [pii]
PST - ppublish
SO - Brain Res 2001 Sep 21;913(2):180-4.