PMID- 11731118
DA - 20011203
DCOM- 20020115
IS - 0367-326X
VI - 72
IP - 8
DP - 2001 Dec
TI - Anxiolytic activity of aerial and underground parts of Passiflora incarnata.
PG - 922-6 AB - The petroleum ether, chloroform, methanol, and water extracts of Passiflora incarnata whole plant and sorted out plant parts have been evaluated for their anxiolytic activity using the elevated plus-maze model in mice. The methanol extracts of leaves, stems, flowers, and whole plant exhibited anxiolytic effects at 100, 125, 200 and 300 mg/kg, respectively. The roots were practically devoid of anxiolytic effects. These results show that roots and flowers of P. incarnata act as natural adulterants by causing a significant increase in the anxiolytic dose. Therefore, separation of these parts is recommended prior to any pharmacological, phytochemical and standardization studies on P. incarnata.
AD - Pharmacognosy Division, University Institute of Pharmaceutical Sciences
[emd]
FAU - Dhawan, K
AU - Dhawan K
FAU - Kumar, S
AU - Kumar S
FAU - Sharma, A
AU - Sharma A
LA - eng
PT - Journal Article
CY - Netherlands
TA - Fitoterapia
JID - 16930290R
RN - 0 (Anti-Anxiety Agents)
RN - 0 (Plant Extracts)
SB - IM
MH - Animal
MH - Anti-Anxiety Agents/administration & dosage/*pharmacology
MH - Dose-Response Relationship, Drug
MH - Female
MH - Male
MH - Maze Learning/*drug effects
MH - Mice
MH - *Passiflora
MH - *Phytotherapy
MH - Plant Components
MH - Plant Extracts/administration & dosage/*pharmacology
MH - Specific Pathogen-Free Organisms
MH - Support, Non-U.S. Gov't
EDAT- 2001/12/04 10:00
MHDA- 2002/01/16 10:01
AID - S0367326X01003227 [pii]
PST - ppublish
SO - Fitoterapia 2001 Dec;72(8):922-6.